Laboratory

Benchmark routinely performs the following activities. Additional services are available upon request. If a service is not listed please contact us as it may be offered.

Assay Development:

ELISA
Receptor/Ligand Interference and Competitive Assay
PCR, including Real-Time PCR
Serology, Membrane Lifts, Precipitations, Antibody Tagging (Fluorescence and Chromagenic), MAT (Microagglutination Test)
Western Blots
HPLC Assays
Cell-Based Assays for Cytokines, Toxins and Cell Receptors
Cell and Virus Stock (Master Seed, Master Cell Stock) Clean-up and Verification
Assay and Methods Validation

Quality Control (Compendial Testing)

Purity
Potency
Identity
Stability
Safety
Adventitious Agent
Mycoplasma

Bio Chemistry

Formulation
Adjuvant Technology
Delivery Systems
Component Testing
Stabilizing Agents

Testing and Validation

Bioreagent Characterization
Reagent Qualification
Reference Characterization
Serum Neutralization
Virus-Isolation
- Indirect-Fluorescent
- Cytopathic-Effect
Mucosal Immune-Response
Hemagglutination and Hemagglutination-Inhibiton
Antiviral-Compound Testing or Ccreening
Cell Pathology and Toxicity Screening

Genetic Testing

PCR and reverse transcriptase PCR
Real-time PCR
Antibiotic Resistance, Growth Inhibition Testing
Gene Isolation and Cloning
Gene Expression Analysis
rDNA Vector Development

Nutraceuticals

Probiotics

Bacteriology

Master Seed Development and Testing
Bacterial/Viral-Growth Promotion;
rDNA or Fermentation-Growth Selection and Optimization
Fermentation-Product Analysis
Bacterial/Viral Neutralization

Immunology

Virology

Master Seed Development and Testing
Viral neutralization
Isolation

Parasitology

Isolation
Purification
Cycling

Cell

Master Cell Stock Creation
Master Cell Stock Testing

Antigen

Recombinants
Flow Cytometry
Mitogenic Compound Screening

Phage

Characterization

Particle Sizing
Digital Microscopy
Antigen Isolation, Purification, Quantitation
In Vitro Reference Antigen Characterization

Process Development

Pre-Manufacturing
- Optimization
Pre-Clinical
- Prelicensing Serials

Analytics

Sample Testing (A proprietary computerized sample-tracking system is used to monitor sample status, inventory location, data collection and sample disposition)